In uncomplicated falciparum malaria, but it is still not recommended for prophylaxis. Amodiaquine may be effective even in areas with chloroquine-resistant P.falciparum. In combination with artesunate as it is being tried as Artemisinin based Combination Therapy (ACT).
Contra Indication
:
Liver damage, severe GI and haematological diseases, eye impairment. Pregnancy.
Caution
:
Injectable form not be used in children below five years. G-6PD deficiency. Peripheral neuropathy, ophthalmic examination required during prolonged therapy.
Side Effect
:
Nausea, vomiting, itching, headache, loss of vision due to retinal damage and corneal deposits. Loss of hearing, rashes, photo allergy, mental disturbances, myopathy and greying of hair.
