Topically for oral, vaginal and cutaneous candidiasis and otomycosis. Most effective for various types of systemic mycoses.
Contra Indication
:
Renal impairment, epilepsy.
Caution
:
Test dose is must before giving intravenously. Adverse reactions can decrease with inclusion of hydrocortisone 0.6 mg/kg body weight in the infusion.
Side Effect
:
Chills, fever, aches, nausea, vomiting and dyspnoea. Thromboflebitis of the injected vein. Nephrotoxicity, (azotemia, reduced g.f.r. acidosis, hypokalemia and inability to concentrate urine). Anaemia due to bone marrow depression. CNS toxicity.
