Antimalarial and anti-inflammatory agent. Effective in the treatment of chloroquine- resistant Falciparum malaria infection. Equally effective as weekly prophylaxis.
Contra Indication
:
Liver damage, severe GI and haematological diseases, eye impairment.Pregnancy.
Caution
:
Injectable form not be used in children below five years. G-6PD deficiency. Peripheral neuropathy, ophthalmic examination required during prolonged therapy.
Side Effect
:
Nausea, vomiting, itching, headache, loss of vision due to retinal damage and corneal deposits. Loss of hearing, rashes, photo-allergy, mental disturbances, myopathy and greying of hair.
